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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c69ba422fe2f51f74221cc03f383c9caab61e3e3a21ee6874530729d8c73d61' 
  AND token = '+UWFaaO2/Nhh13WmhyVq0S/uWDcGGIKbvcLzlvX8mNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}