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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac72a09267efb9f61dd4553ddfd161760f3610c3888fbf5a0360b2f354b8740a' 
  AND token = 'x0PFAP+kTa4q7AJbFOUUpbjgywqXC6kRVih54SibnkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}