SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a3bc432e779f4ca16361a99dc28c426093fdf230266892830268ddf21a0442' 
  AND token = 'tiM378lv4a4ieSa3Bu+7UM8h3HFeEo/pn0h815+taLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}