SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3625bfe6d49f599ea69b5f91c059cd9ae630f40e4e540e2289750d77de054708' 
  AND token = 'US5LfFlGJubTJTOFZv1UYCXJWUpF4zY8frY65HonJI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}