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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9893a3e10193b87229972b7b87ff2f103c34190e87f789c47b90a118f84880' 
  AND token = 'F9r4yrMXUP6KrQlgfamSHPpF3bmHcKCZWrOZd1pYZkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}