SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e820425133b5556bbf1fcf7ae7e440a9eb14295503b17dc6f66235213b63e2' 
  AND token = 'PpNua8snemaBuqs3dPRs2pgnqkWKT1VTDEVwfRi22xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}