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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99817045c6e1a6ce64ee173f6b37aa229b4221387fd29d5d06e9483b88ef702a' 
  AND token = 'N69+1VojId0NbqFXZEHyXZ9ceIYJg+go7i3uLSM38Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}