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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd295a0f61106228eaba038a5a4d2d39cdce5bc202be2c42f384b8cde4ced59d0' 
  AND token = 'aQ104v+IGL3N4ueUncISSOpQa2usHeYM8R6bZZaAy2w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}