SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01185e4f0e11643a2aa6ea941d3a11500c8bc4175bcca9f823264e40273a1b1b' 
  AND token = 'zylAp5DrM23rH/Px/m2IvpMmZy0BZbQorsDEfCn7/2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}