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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e7cbf807220e3c1d7e8981a2833169d3165d5bc4920e8dd2e0fdf1e5785e44' 
  AND token = 'JrW0ACinU/ZE7Qt1u7SjEg68PXK1EV6w1/DofRxNqxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}