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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c4e2bcb622785c3b241394c07d29babe9bebbef761841f61ed59da8ed0e61b8' 
  AND token = 'zTjB9wRj/s0j+kQRhcCsZtOaDE6Cf5X/06xnN25NOYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}