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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca61e041839ce0d465922452c4e0c6e842714e2e7ad8bfbc1934bdb31452b1f' 
  AND token = 'kkeHOlbRY95CmbbtXDBV1D/ml1990sbAumcxCWIhhYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}