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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8263e9e64945012d39ed7fe527655ff7fbff68daf840fd743ee6ed4f4526d4aa' 
  AND token = 'c55EV7C2s9eGWvgVKTK9q0s8KgkiB6lIToAkRaY9O3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}