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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf4fb5f1e4db6a53a70380e103778ab369ce87a5e5beecc3727de6d56eef78e6' 
  AND token = 'BgMTNKeBVinamnC3ZrQPpxpsMSXRds+7U9XWlyGwkDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}