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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '026249a0c5c2a40d3e827e7673bd3c30b64b3fb5d8c09f38c8eeda7389a8db81' 
  AND token = 'Qgy9xC9xBCp4yLH1C0IDfbA2f3c6SYMK6viYkd90Xtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}