SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce83a3774246641a3d64fbbae0d6ed6d0ea4fe6630f835035947877b97d80e7' 
  AND token = 'TKsj+RMqrOAgRyPMXdSaxaR6Hc60mGZUboOAn3rL/qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}