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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7b0ef68616c9f619c553884c429af04cf1f95db8eebe7d3307205182c16f31' 
  AND token = 'Z4vyh24P+bnn2EDJFkoaehcpsD9QDiz38FyXMf8ZFM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}