SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a62a54eb8ca1f00426279a773685d3c127ec8f1162cbcb10a3e8a42acccca0fd' 
  AND token = 'TwsagpdGZf7gDKh/VP+E+PpQGpHF06Wb/vHGtFN8pvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}