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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3ac8192ba1b2e6b6c54fd220f78a806170ac97eea49f49431eaac113029e6a' 
  AND token = 'cO9pRbwNIAk2eShnRncHs6KPkCnxUXSU/anB21YOJj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}