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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d9581a6b9561c15ab14ed7e32ac78ff053327a2cefb658d74ef51db2e863f6' 
  AND token = 'djgNdW4ULwpcuw9Rpc+AYd0DJH3d6B0QbT6MqEPvPeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}