SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a012905e09ef29e82a65f9f28fcbef77f9c9f92815c6bc35b9b7a794a4540352' 
  AND token = 'q36XoY9mf+qwGzf10TG3bRSCiODm1vkLoAbIBdgS4KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}