SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f3c5df47dc1ff562799e967e9da23b7c299e9da9c03d7d053d7e4703a70ffc' 
  AND token = 'Uj2wCpp5GPp54j0j67CQx9iSvN06WeS0SEB/bBstmfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}