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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43be065e86fcc639cc0565547bf21838cfae41131287ee98a7a5f7f22808a7cd' 
  AND token = 'Gkr+TqhTQ7ETbZ36a0eg84J/ru/R7Qz+pu69042PNI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}