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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d7a1cdd195bffdc2bfb5324bd03053bf798eee3947152522f46ea5b2f81382' 
  AND token = '1I4VPZBlKBQCcvh84TL1f/WQSiEAFaEL5Mp5TSjCoTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}