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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f99622086b3c75d56b96ac941c2d8574ed3038e019195662eb370c421b831b91' 
  AND token = 'fex7MADx4dXnyh6NJr1/VhBMjEjBXICrl/pU1y1rI24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}