SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6b8c74df7770e14b54426b52717101c6e399c7da6c204f91ba314661ee2e31' 
  AND token = 'W7kLTGq6SfRIEOmQGRsm//2SaGX7YqXHf5XDWhJkl6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}