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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4372e789bbc612f741c4b2b99a84f0fdc4afcb9548a2dae23f05f2c85c245ec' 
  AND token = 'j8KmIkHUBvHBqAAXs8xFhnA4TAccr6RizeqRK5FW8Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}