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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45cd92f3219826ef17040c6db04a2352e223fe93416073432dc7bffc86fa78df' 
  AND token = 'v8bfadb1dNTcAMQ5umHW+P6Wqroo38m7u9B2GUtIzqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}