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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac728cabb61b29e22cb2afbf2da82266cb2bfd4e053a4d18b55cd47512d7d6f' 
  AND token = 'nK6UoXgQs/BYa4orcq0IIVsRncIjcM2B7gsyUOlXptY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}