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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '852d85d9fe1d9e75def9cb25c780b64d9ac1dbbb5c335f7254cdf251d154747e' 
  AND token = 'qJEXA+PIiFk+2s9Pu8DJJcByduVZYRc6FCkaJaVo9hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}