SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768f9cea3cd2ef7a022693d4f1d79165b87d7906cc3fc120a955379564202261' 
  AND token = 'TGkk6GvywftecvhW+pHReHZ1HfZJEq1q3di9maaR0SY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}