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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c741a9c7e33155724b5d5213e059f6e64c6f5e3cea573a63230012acab7ed12' 
  AND token = 'ioieg9kAD8yScDecQWYpmIlEL4eyWUw8HLSGGGg1DWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}