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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd70f8a89c64cfcde808af6a82b146e3d80dcca0c7ea17f725d884affa99a315a' 
  AND token = 'yyXPjHD4gRSoVmHNEu9RfbtMcZ4Y3t/oUkpq7TJaj8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}