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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e61d9dca5ffb9f1abfa62b54d33b2cbd19cc47584b9b310391eb5cf1fca3eeb4' 
  AND token = 'ZA22HQDG1hGopFdDMFGnIJxokVnIIrnVUgXmpyY2gkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}