SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36fb72fefe10aa6889f386387797527c5456088653f11ac93b82a6c9af209e0c' 
  AND token = 'vnV9gJEABSs1uJXHss/P7/Kr0FoCO5UM4d19SNIJVNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}