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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e4861a74847a21b13e21bb476dfe44af7b7d610f4d5d2a44ab1670560bad61' 
  AND token = 'z/g425EczkybmHPFzs/sj+vSuUgklp4mUZJR+Sp87rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}