SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ec540e1f8aa48e97dae7019a7773b0b01326e12645cf20569ef4e72a281656' 
  AND token = 'BRb6dBYi9vr1qvX/abQdJMliJhfBHdJlqwbEN4DkFIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}