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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73d3fb5d3fd93f1135c6de763109210eee852d1143491e04002aeaf1f049ed68' 
  AND token = 'Y07ACfzRmPeshMsHrpEavbk5xvfvYrfxFzvWfi0P3LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}