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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c91eed7f8976c9b3a451b33ac1e12391b1c93d1241d5808b34520453175be6' 
  AND token = 'NeZOS0wmYnOgL0NxpYtq+SDKV6nooXssndo4kJx/m9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}