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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '411e99023c3940c4f0a7dba337e869c9ba1ec6a420eb71a1c727ca58c8537f1c' 
  AND token = 'gxisHU6nIXtHLcDG8qsFNlSs0I4BkH7o0TEdOU49Pe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}