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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5fe8cd46bc18d15dccf9e491ec4c492a9c1c6ea9f7c5427bafc5e5296e76c4c' 
  AND token = 'UX+LvSGkiOTBLy7+jP9VczTEeEpHDg4Gwjk5TdX6OAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}