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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a9ab8523925581268b7592d75b9cdbcaf345243ed4217102545a437ced64294' 
  AND token = 'SS6Biqiug+WROy14i1XD1WPNyYEO0QWkYzPZbwSAtHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}