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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7a064ef33fc055b55a49f016caf057d521bb8e7e954adb01a0f1268cb6406b' 
  AND token = 'WE+Ay3kJ3KIKhpVEo60pRfnfyX4K8rTgd8p+IXQk3UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}