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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f5a8b088e61270f10b537cdcaa959a21da681d940b4ac824f81760372bc7cf' 
  AND token = 'UW7fFaE1L9sQDmT5hY4mD4jff6S3prOLzwvEUmqjb6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}