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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c5f11f543de923737a7fbcb244222851829de80113bc8503994e3a08be524e' 
  AND token = 'u4/tF4dFdSypvfo127aE/sDFq5Wk+/BaU2wiUatrbQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}