SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c67c60756d7d085f63d4d160c574bec7bf50f77c3136801554d62b74410a3955' 
  AND token = '2g8myKkHXOrAJCf5dOGgQ8FxCcR8X2CjChhR8+PMMdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}