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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0399211fa2f26c10eac469d4c99a0f8e27a9ba4e438feddfcfc56981bf80de35' 
  AND token = 'hrlomAsZpn9UYw0dw5nxYRjNtvdir/WOuLoJDn8Rp/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}