SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce90e1a6a023e65980d271cd8f1d00bdda0acb10dbf9c6766b69157b1754edc' 
  AND token = 'JCHLUQhfAHMaliU+RqKZDuEJAkjfVFFzZinHW6s6iRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}