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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62e953863c074ed1130f7e6a1051c934723bdeab735b538d91b2e77e5f375d89' 
  AND token = 'u6kCDW3ylUhW6xP88hQ3wDltKF7CkzRySASfscfkMvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}