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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36366a1291390f7e7e3ca47330184ec452ee43e73be30d251118d948eaaf5bdf' 
  AND token = '4KzpVyiExlR0yBXRjoVR5Knhtmox7GFDDAhVOJsk3Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}